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GO Related Resource Count : 49,239
GO Term Detail
GO ID: GO:0003918
Term Information
Category
molecular_function
Name
DNA topoisomerase type II (ATP-hydrolyzing) activity
Synonyms
deoxyribonucleate topoisomerase, deoxyribonucleic topoisomerase activity, DNA topoisomerase (ATP-hydrolysing), DNA topoisomerase II, DNA topoisomerase IV activity, DNA topoisomerase type II activity, topoisomerase, topoisomerase II, type II DNA topoisomerase activity
Definition
Catalysis of a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2.
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