Home > 分離済み変異体 > tm238

分離済み変異体

Allele Name		tm238
Allele Type		通常株
Sequence Name		C36F7.1
Gene Name		irx-1
Worm Base	Allele Name	tm238
	Gene Name	irx-1
	Sequence	C36F7.1
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		homozygous viable; Dr. H. Sawa: 0% Psa (n=98); Dr. J-L. Bessereau: deletion is within an intron and does not affect gene expression. Dr. D. Portman: male tail appears grossly normal. Dr. D.M. Miller: no gross phenotype is found unlike tm3354.
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		1604/1605-1953/1954 (349 bp deletion)
Chromosome		I
Putative gene structure		complement (join(325..552, 1053..1412, 2008..2469, 3002..3022))
Map position		3.78
Balancer
Map position of balancer
Sequence of primers		IntFwd:ATGTACAAGCACGCACGGT,ExtFwd:CTGAGCGTCACGACAGGATA,IntRev:GCTTATCACTGAATCGCTCC,ExtRev:GTTGTTGAACATAAGGTCCC
Distributed lab
Depositor		Dr. S. Mitani
References		Please submit your publication McDiarmid TA, Belmadani M, Liang J, Meili F, Mathews EA, Mullen GP, Hendi A, Wong WR, Rand JB, Mizumoto K, Haas K, Pavlidis P, Rankin CH. Systematic phenomics analysis of autism-associated genes reveals parallel networks underlying reversible impairments in habituation. Proc Natl Acad Sci U S A 2020 117(1) 656-667  [ PubMed ID = 31754030 ] [ RRC reference ] Mills H, Wragg R, Hapiak V, Castelletto M, Zahratka J, Harris G, Summers P, Korchnak A, Law W, Bamber B, Komuniecki R. Monoamines and neuropeptides interact to inhibit aversive behaviour in Caenorhabditis elegans. EMBO J 2012 31(3) 667-78  [ PubMed ID = 22124329 ] [ RRC reference ]