 Tabs(ALL, DNA, BLAST, GO, Taxonomy, DO, Reference) are clickable.
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Reference Related Resource Count: 23,108
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Associated Resources List
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Category: targeted mutation
| Strain Name : |
B6;129P2-Sema4d<tm1Kik>/Rbrc |
| Gene : |
Sema4d,Sema4D,neo |
| Species : |
Mus musculus |
| Conditions for use : |
Recovered litters from cryopreserved embryos (2 to 4 months),Cryopreserved embryos (within 1 month) |
| Status : |
Frozen embryos |
| Taxonomy : |
Mus musculus
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| Reference : |
Zhu Z, Luo Y, Yu J, Gao J, Zhang Y, Xiao C, Zhang C, Wang G, Liu Y, Fu M, Yao X, Li W. (2016) Sema4D is required in both the adaptive and innate immune responses of contact hypersensitivity. Mol Immunol 78 98-104
Zhang C, Qiao H, Guo W, Liu Y, Yang L, Liu Y, Jin B, Fu M, Wang G, Li W. (2019) CD100-plexin-B1 induces epithelial-mesenchymal transition of head and neck squamous cell carcinoma and promotes metastasis. Cancer Lett 455 1-13
Xiao C, Luo Y, Zhang C, Zhu Z, Yang L, Qiao H, Fu M, Wang G, Yao X, Li W. (2020) Negative regulation of dendritic cell activation in psoriasis mediated via CD100-plexin-B2. J Pathol 250(4) 409-419
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Category: targeted mutation
Category: targeted mutation
| Strain Name : |
B6.Cg-Fyn<tm1Yik>/TyagRbrc |
| Gene : |
Fyn,lacZ,neo |
| Species : |
Mus musculus |
| Disease : |
Fluorescent Proteins/lacZ System |
| Conditions for use : |
Recovered litters from cryopreserved embryos (2 to 4 months),Cryopreserved sperm (within 1 month),Cryopreserved embryos (within 1 month) |
| Status : |
Frozen embryos,Frozen sperm |
| Taxonomy : |
Mus musculus
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| Reference : |
Miyata N, Gon Y, Nunomura S, Endo D, Yamashita K, Matsumoto K, Hashimoto S, Ra C. (2008) Inhibitory effects of parthenolide on antigen-induced microtubule formation and degranulation in mast cells. Int Immunopharmacol 8(6) 874-80
Nunomura S, Gon Y, Yoshimaru T, Kashiwakura J, Kawakami T, Ra C. (2010) FcepsilonRI beta-chain ITAM amplifies PI3K-signaling to ensure synergistic degranulation response via FcepsilonRI and adenosine receptors. Eur J Immunol 40(4) 1205-17
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Category: targeted mutation
| Strain Name : |
ICR.Cg-Nrp1<tm1Hfu>/HfuRbrc |
| Gene : |
Nrp1,neo |
| Species : |
Mus musculus |
| Disease : |
Cardiovascular Research,Developmental Biology Research,Hematological Research,Immunology and Inflammation Research,Neurobiology Research,covid19_infection |
| Conditions for use : |
Recovered litters from cryopreserved embryos (2 to 4 months),Cryopreserved sperm (within 1 month),Cryopreserved embryos (within 1 month) |
| Status : |
Frozen embryos,Frozen sperm |
| Taxonomy : |
Mus musculus
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| Reference : |
Hatanaka Y, Matsumoto T, Yanagawa Y, Fujisawa H, Murakami F, Masu M. (2009) Distinct roles of neuropilin 1 signaling for radial and tangential extension of callosal axons. J Comp Neurol 514(3) 215-25
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Category: targeted mutation
| Strain Name : |
C.Cg-Hivep2<tm1Sis>/Rbrc |
| Gene : |
Hivep2,neo |
| Species : |
Mus musculus |
| Disease : |
Immunology and Inflammation Research |
| Conditions for use : |
Recovered litters from cryopreserved embryos (2 to 4 months) |
| Status : |
Frozen embryos |
| Taxonomy : |
Mus musculus
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| Reference : |
Takao K, Kobayashi K, Hagihara H, Ohira K, Shoji H, Hattori S, Koshimizu H, Umemori J, Toyama K, Nakamura HK, Kuroiwa M, Maeda J, Atsuzawa K, Esaki K, Yamaguchi S, Furuya S, Takagi T, Walton NM, Hayashi N, Suzuki H, Higuchi M, Usuda N, Suhara T, Nishi A, Matsumoto M, Ishii S, Miyakawa T. (2013) Deficiency of schnurri-2, an MHC enhancer binding protein, induces mild chronic inflammation in the brain and confers molecular, neuronal, and behavioral phenotypes related to schizophrenia. Neuropsychopharmacology 38(8) 1409-25
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Category: targeted mutation
| Strain Name : |
B6;129-Dffb<tm1Osa>/OsaRbrc |
| Gene : |
Dffb,neo |
| Species : |
Mus musculus |
| Conditions for use : |
Recovered litters from cryopreserved embryos (2 to 4 months),Cryopreserved sperm (within 1 month),Cryopreserved embryos (within 1 month) |
| Status : |
Frozen embryos,Frozen sperm |
| Taxonomy : |
Mus musculus
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| Reference : |
Gao L, Huang K, Jiang DS, Liu X, Huang D, Li H, Zhang XD, Huang K. (2015) Novel role for caspase-activated DNase in the regulation of pathological cardiac hypertrophy. Hypertension 65(4) 871-81
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Category: targeted mutation
| Strain Name : |
B6;129-Dnase2a<tm1Osa>/OsaRbrc |
| Gene : |
Dnase2a,loxP,neo |
| Species : |
Mus musculus |
| Disease : |
Mouse Models for Human Disease |
| Conditions for use : |
Recovered litters from cryopreserved embryos (2 to 4 months),Cryopreserved sperm (within 1 month),Cryopreserved embryos (within 1 month) |
| Status : |
Frozen embryos,Frozen sperm |
| Taxonomy : |
Mus musculus
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| Reference : |
Chan MP, Onji M, Fukui R, Kawane K, Shibata T, Saitoh S, Ohto U, Shimizu T, Barber GN, Miyake K. (2015) DNase II-dependent DNA digestion is required for DNA sensing by TLR9. Nat Commun 6 5853
Ahn J, Gutman D, Saijo S, Barber GN. (2012) STING manifests self DNA-dependent inflammatory disease. Proc Natl Acad Sci U S A 109(47) 19386-91
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Category: targeted mutation
Category: targeted mutation
Category: targeted mutation
| Strain Name : |
B6.Cg-Mapt<tm1.1(MAPT)Tcs> App<tm1(NL)Tcs> |
| Gene : |
Mapt,App,MAPT,Frt,loxP |
| Species : |
Mus musculus |
| Disease : |
Cre/loxP system,FLP/frt system |
| Conditions for use : |
Recovered litters from cryopreserved embryos (2 to 4 months),Cryopreserved sperm (within 1 month),Cryopreserved embryos (within 1 month) |
| Status : |
Frozen embryos,Frozen sperm |
| Taxonomy : |
Mus musculus
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| Reference : |
Hiroki Sasaguri, Shoko Hashimoto, Naoto Watamura, Kaori Sato, Risa Takamura, Kenichi Nagata, Satoshi Tsubuki, Toshio Ohshima, Atsushi Yoshiki, Kenya Sato, Wakako Kumita, Erika Sasaki, Shinobu Kitazume, Per Nilsson, Bengt Winblad, Takashi Saito, Nobuhisa Iwata, Takaomi C. Saido (2022) Recent Advances in the Modeling of Alzheimer’s Disease Frontiers Neuroscience 16
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Category: targeted mutation
| Strain Name : |
B6.Cg-Mapt<tm1.1(MAPT)Tcs> App<tm2(NL-F)Tcs> |
| Gene : |
Mapt,App,Frt,loxP,MAPT |
| Species : |
Mus musculus |
| Disease : |
Cre/loxP system,FLP/frt system |
| Conditions for use : |
Recovered litters from cryopreserved embryos (2 to 4 months),Cryopreserved sperm (within 1 month),Cryopreserved embryos (within 1 month) |
| Status : |
Frozen embryos,Frozen sperm |
| Taxonomy : |
Mus musculus
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| Reference : |
Hiroki Sasaguri, Shoko Hashimoto, Naoto Watamura, Kaori Sato, Risa Takamura, Kenichi Nagata, Satoshi Tsubuki, Toshio Ohshima, Atsushi Yoshiki, Kenya Sato, Wakako Kumita, Erika Sasaki, Shinobu Kitazume, Per Nilsson, Bengt Winblad, Takashi Saito, Nobuhisa Iwata, Takaomi C. Saido (2022) Recent Advances in the Modeling of Alzheimer’s Disease Frontiers Neuroscience 16
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Category: targeted mutation
| Strain Name : |
B6.129P2-Prkcd<tm1Kin> |
| Gene : |
Prkcd,neo |
| Species : |
Mus musculus |
| Conditions for use : |
Recovered litters from cryopreserved sperm (2 to 4 months),Cryopreserved sperm (within 1 month) |
| Status : |
Frozen embryos,Frozen sperm |
| Taxonomy : |
Mus musculus
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| Reference : |
Chichger H, Grinnell KL, Casserly B, Chung CS, Braza J, Lomas-Neira J, Ayala A, Rounds S, Klinger JR, Harrington EO. (2012) Genetic disruption of protein kinase Cδ reduces endotoxin-induced lung injury. Am J Physiol Lung Cell Mol Physiol 303(10) L880-8
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Category: targeted mutation
Category: targeted mutation
| Strain Name : |
B6;129P2-Ptpn7<tm1Bwz>/Rbrc |
| Gene : |
Ptpn7,neo |
| Species : |
Mus musculus |
| Conditions for use : |
Recovered litters from cryopreserved embryos (2 to 4 months),Cryopreserved sperm (within 1 month),Cryopreserved embryos (within 1 month) |
| Status : |
Frozen embryos,Frozen sperm |
| Taxonomy : |
Mus musculus
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| Reference : |
Wang N, Langfelder P, Stricos M, Ramanathan L, Richman JB, Vaca R, Plascencia M, Gu X, Zhang S, Tamai TK, Zhang L, Gao F, Ouk K, Lu X, Ivanov LV, Vogt TF, Lu QR, Morton AJ, Colwell CS, Aaronson JS, Rosinski J, Horvath S, Yang XW. (2022) Mapping brain gene coexpression in daytime transcriptomes unveils diurnal molecular networks and deciphers perturbation gene signatures. Neuron 110(20) 3318-3338.e9
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Category: targeted mutation
| Strain Name : |
B6.129P2-Emx1<tm1(cre)Ito>/ItoRbrc |
| Gene : |
Emx1,neo,Frt,nls,cre, |
| Species : |
Mus musculus |
| Disease : |
Cell Biology Research,Cre/loxP system,FLP/frt system,Neurobiology Research |
| Conditions for use : |
Recovered litters from cryopreserved embryos (2 to 4 months),Cryopreserved sperm (within 1 month),Cryopreserved embryos (within 1 month) |
| Status : |
Frozen embryos,Frozen sperm |
| Taxonomy : |
Mus musculus
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| Reference : |
Kita A, Imayoshi I, Hojo M, Kitagawa M, Kokubu H, Ohsawa R, Ohtsuka T, Kageyama R, Hashimoto N. (2007) Hes1 and Hes5 control the progenitor pool, intermediate lobe specification, and posterior lobe formation in the pituitary development. Mol Endocrinol 21(6) 1458-66
Imayoshi I, Shimogori T, Ohtsuka T, Kageyama R. (2008) Hes genes and neurogenin regulate non-neural versus neural fate specification in the dorsal telencephalic midline. Development 135(15) 2531-41
Kinameri E, Inoue T, Aruga J, Imayoshi I, Kageyama R, Shimogori T, Moore AW. (2008) Prdm proto-oncogene transcription factor family expression and interaction with the Notch-Hes pathway in mouse neurogenesis. PLoS One 3(12) e3859
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Category: targeted mutation
| Strain Name : |
B6.129P2-Ptprt<tm1Sata>/SataRbrc |
| Gene : |
Ptprt,neo |
| Species : |
Mus musculus |
| Conditions for use : |
Recovered litters from cryopreserved embryos (2 to 4 months),Cryopreserved sperm (within 1 month),Cryopreserved embryos (within 1 month) |
| Status : |
Frozen embryos,Frozen sperm |
| Taxonomy : |
Mus musculus
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| Reference : |
Feng X, Scott A, Wang Y, Wang L, Zhao Y, Doerner S, Satake M, Croniger CM, Wang Z. (2014) PTPRT regulates high-fat diet-induced obesity and insulin resistance. PLoS One 9(6) e100783
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Category: targeted mutation
| Strain Name : |
B6.Cg-Aqp4<tm1.1(GFP)Mysi>/5Rbrc |
| Gene : |
Aqp4,EGFP,loxP,Frt |
| Species : |
Mus musculus |
| Disease : |
Cre/loxP system,FLP/frt system,Fluorescent Proteins/lacZ System |
| Conditions for use : |
Recovered litters from cryopreserved sperm (2 to 4 months),Cryopreserved sperm (within 1 month) |
| Status : |
Frozen embryos,Frozen sperm |
| Taxonomy : |
Mus musculus
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| Reference : |
Michael Nicosia, Juyeun Lee, Ashley Beavers, Danielle Kish, George W Farr, Paul R McGuirk, Marc F Pelletier, Justin D Lathia, Robert L Fairchild, Anna Valujskikh (2023) Water channel Aquaporin 4 is required for T cell receptor mediated lymphocyte activation Journal of Leukocyte Biology
Z Heřmanová () The Role of Aquaporin 4 channels and Transient Receptor Potential Vanilloid 4 channels in astrocytic swelling. Univerzita Karlova
Nicosia M, Miyairi S, Beavers A, Farr GW, McGuirk PR, Pelletier MF, Valujskikh A. (2019) Aquaporin 4 inhibition alters chemokine receptor expression and T cell trafficking. Sci Rep 9(1) 7417
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Category: targeted mutation
| Strain Name : |
B6.129P2-Map2k4<tm1Pngr>/Rbrc |
| Gene : |
Map2k4,neo |
| Species : |
Mus musculus |
| Disease : |
Cell Biology Research |
| Conditions for use : |
Recovered litters from cryopreserved embryos (2 to 4 months),Cryopreserved sperm (within 1 month),Cryopreserved embryos (within 1 month) |
| Status : |
Frozen embryos,Frozen sperm |
| Taxonomy : |
Mus musculus
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| Reference : |
Sugiyama D, Kulkeaw K, Mizuochi C, Horio Y, Okayama S. (2011) Hepatoblasts comprise a niche for fetal liver erythropoiesis through cytokine production. Biochem Biophys Res Commun 410(2) 301-6
Sugiyama D, Kulkeaw K, Mizuochi C. (2013) TGF-beta-1 up-regulates extra-cellular matrix production in mouse hepatoblasts. Mech Dev 130(2-3) 195-206
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Category: targeted mutation
Category: targeted mutation
| Strain Name : |
B6;129S7-Hey1<tm1Kkb>/YsaRbrc |
| Gene : |
Hey1,loxP,lacZ,neo,IRES |
| Species : |
Mus musculus |
| Disease : |
Cell Biology Research,Cre/loxP system |
| Conditions for use : |
Recovered litters from cryopreserved embryos (2 to 4 months),Cryopreserved sperm (within 1 month),Cryopreserved embryos (within 1 month) |
| Status : |
Frozen embryos,Frozen sperm |
| Taxonomy : |
Mus musculus
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| Reference : |
Harada Y, Yamada M, Imayoshi I, Kageyama R, Suzuki Y, Kuniya T, Furutachi S, Kawaguchi D, Gotoh Y. (2021) Cell cycle arrest determines adult neural stem cell ontogeny by an embryonic Notch-nonoscillatory Hey1 module. Nat Commun 12(1) 6562
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