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Resource count: 6,594,868

Resource Information Strain No : RBRC01725

Resource Information
Organism Mice
strain or clone Strain
Category targeted mutation
Resource name RBRC01725
Availability Available
Features
Strain Name : B6;129-Dnase2a<tm1Osa>/OsaRbrc
Gene : Dnase2a,loxP,neo
Species : Mus musculus
Disease : Mouse Models for Human Disease
Conditions for use : Recovered litters from cryopreserved embryos (2 to 4 months),Cryopreserved sperm (within 1 month),Cryopreserved embryos (within 1 month)
Status : Frozen embryos,Frozen sperm
Taxonomy : Mus musculus
Reference : Chan MP, Onji M, Fukui R, Kawane K, Shibata T, Saitoh S, Ohto U, Shimizu T, Barber GN, Miyake K. (2015) DNase II-dependent DNA digestion is required for DNA sensing by TLR9. Nat Commun 6 5853
Ahn J, Gutman D, Saijo S, Barber GN. (2012) STING manifests self DNA-dependent inflammatory disease. Proc Natl Acad Sci U S A 109(47) 19386-91
Resouce detail information
(request form)
http://www2.brc.riken.jp/lab/animal/detail.php?brc_no=RBRC01725

Distributors information
Organization Experimental Animal Division, RIKEN BioResource Research Center
Person in charge YOSHIKI Atsushi
Postal Code 305-0074
Address 3-1-1 Koyadai, Tsukuba, Ibaraki, Japan
Phone 029-836-5264
FAX 029-836-9010
E-mail animal@brc.riken.jp
URL https://mus.brc.riken.jp
Other information