Home > 分離済み変異体 > tm252

分離済み変異体

Allele Name		tm252
Allele Type		通常株
Sequence Name		C39E6.4
Gene Name		mls-2
Worm Base	Allele Name	tm252
	Gene Name	mls-2
	Sequence	C39E6.4
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		homozygous viable. Dr. J. Liu: Development 132, 4119-4130 (2005). Dr. P. Sengupta: devective development of chemosensory neurons.
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		20622/20623-T-21102/21103 (480 bp deletion + 1 bp insertion)
Chromosome		X
Putative gene structure		complement(join(20095..20257, 20304..20530, 20577..20665, 20719..20841, 22155..22390, 22447..22634))
Map position		-7
Balancer
Map position of balancer
Sequence of primers		ExtFwd:GTCGGCCCTATCAAAGATGA,IntFwd:GTGAAGTACAATGACTACGAC,IntRev:CTCCGAATCTCAGAACACCC,ExtRev:AAACATGAGCAACCCAGGTC
Distributed lab
Depositor		Dr. S. Mitani
References		Please submit your publication Godini R, Pocock R. Characterization of the Doublesex/MAB-3 transcription factor DMD-9 in Caenorhabditis elegans. G3 (Bethesda) 2023 13(2)   [ PubMed ID = 36454093 ] [ RRC reference ] Hsieh YW, Xiong R, Chuang CF. Synergistic roles of homeodomain proteins UNC-62 homothorax and MLS-2 HMX/NKX in the specification of olfactory neurons in Caenorhabditis elegans. Genetics 2021 219(2)   [ PubMed ID = 34849889 ] [ RRC reference ] Kim K, Kim R, Sengupta P. The HMX/NKX homeodomain protein MLS-2 specifies the identity of the AWC sensory neuron type via regulation of the ceh-36 Otx gene in C. elegans. Development 2010 137(6) 963-74  [ PubMed ID = 20150279 ] [ RRC reference ] Jiang Y, Horner V, Liu J. The HMX homeodomain protein MLS-2 regulates cleavage orientation, cell proliferation and cell fate specification in the C. elegans postembryonic mesoderm. Development 2005 132(18) 4119-30  [ PubMed ID = 16107479 ] [ RRC reference ]