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Resource Information landlocked

Resource Information
Organism	Zebrafish
strain or clone	Strain
Category	Mutant
Resource name	landlocked
Availability	Available
Features	Allele : rw16 Information : Mutant shows highly specific defects in the caudal migration of the nVII motor neurons. The maternal and zygotic mutant shows defects in convergent extension (CE) movements during gastrulation. rw16 allele has a point mutation (amino acid substitution) in the first PDZ domain of Scrb1. Gene : scribble1 Publications : Wada H et al (2005) Development 132(10),2273-85 Taxonomy : Siluriformes Reference : Sun SD, Purdy AM, Walsh GS. (2016) Planar cell polarity genes Frizzled3a, Vangl2, and Scribble are required for spinal commissural axon guidance. BMC Neurosci 17(1) 83 McArthur KL, Fetcho JR. (2017) Key Features of Structural and Functional Organization of Zebrafish Facial Motor Neurons Are Resilient to Disruption of Neuronal Migration. Curr Biol 27(12) 1746-1756.e5
Resouce detail information (request form)	http://shigen.nig.ac.jp/zebrafish/strainDetailAction.do?strainId=15

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Distributors information
Organization	Developmental Gene Regulation. RIKEN Brain Science Institute
Person in charge	OKAMOTO Hitoshi
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E-mail	hitoshi.okamoto@riken.jp
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