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Resource count: 6,595,109

Resource Information Strain No : RBRC00904

Resource Information
Organism Mice
strain or clone Strain
Category targeted mutation
Resource name RBRC00904
Availability Available
Features
Strain Name : C.129S2-Pdcd1<tm1Hon>/HonRbrc (N12)
Gene : Pdcd1,neo
Species : Mus musculus
Disease : Immunology and Inflammation Research
Conditions for use : Live mouse (1 to 3 months),Cryopreserved sperm (within 1 month),Cryopreserved embryos (within 1 month)
Status : Live mice,Frozen embryos,Frozen sperm
Taxonomy : Mus musculus
Reference : Ding ZC, Blazar BR, Mellor AL, Munn DH, Zhou G. (2010) Chemotherapy rescues tumor-driven aberrant CD4+ T-cell differentiation and restores an activated polyfunctional helper phenotype. Blood 115(12) 2397-406
Ding ZC, Blazar BR, Mellor AL, Munn DH, Zhou G. (2010) Chemotherapy rescues tumor-driven aberrant CD4+ T-cell differentiation and restores an activated polyfunctional helper phenotype. Blood 115(12) 2397-406
Ding ZC, Lu X, Yu M, Lemos H, Huang L, Chandler P, Liu K, Walters M, Krasinski A, Mack M, Blazar BR, Mellor AL, Munn DH, Zhou G. (2014) Immunosuppressive myeloid cells induced by chemotherapy attenuate antitumor CD4+ T-cell responses through the PD-1-PD-L1 axis. Cancer Res 74(13) 3441-53
Ding ZC, Lu X, Yu M, Lemos H, Huang L, Chandler P, Liu K, Walters M, Krasinski A, Mack M, Blazar BR, Mellor AL, Munn DH, Zhou G. (2014) Immunosuppressive myeloid cells induced by chemotherapy attenuate antitumor CD4+ T-cell responses through the PD-1-PD-L1 axis. Cancer Res 74(13) 3441-53
Ding ZC, Huang L, Blazar BR, Yagita H, Mellor AL, Munn DH, Zhou G. (2012) Polyfunctional CD4⁺ T cells are essential for eradicating advanced B-cell lymphoma after chemotherapy. Blood 120(11) 2229-39
Ding ZC, Huang L, Blazar BR, Yagita H, Mellor AL, Munn DH, Zhou G. (2012) Polyfunctional CD4⁺ T cells are essential for eradicating advanced B-cell lymphoma after chemotherapy. Blood 120(11) 2229-39
Resouce detail information
(request form)
http://www2.brc.riken.jp/lab/animal/detail.php?brc_no=RBRC00904

Distributors information
Organization Experimental Animal Division, RIKEN BioResource Research Center
Person in charge YOSHIKI Atsushi
Postal Code 305-0074
Address 3-1-1 Koyadai, Tsukuba, Ibaraki, Japan
Phone 029-836-5264
FAX 029-836-9010
E-mail animal@brc.riken.jp
URL https://mus.brc.riken.jp
Other information