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Resource count: 6,595,109
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Resource Information
Strain No :
RBRC00904
Organism |
Mice |
strain or clone |
Strain |
Category |
targeted mutation |
Resource name |
RBRC00904 |
Availability |
Available
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Features |
Strain Name : |
C.129S2-Pdcd1<tm1Hon>/HonRbrc (N12) |
Gene : |
Pdcd1,neo |
Species : |
Mus musculus |
Disease : |
Immunology and Inflammation Research |
Conditions for use : |
Live mouse (1 to 3 months),Cryopreserved sperm (within 1 month),Cryopreserved embryos (within 1 month) |
Status : |
Live mice,Frozen embryos,Frozen sperm |
Taxonomy : |
Mus musculus
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Reference : |
Ding ZC, Blazar BR, Mellor AL, Munn DH, Zhou G. (2010) Chemotherapy rescues tumor-driven aberrant CD4+ T-cell differentiation and restores an activated polyfunctional helper phenotype. Blood 115(12) 2397-406
Ding ZC, Blazar BR, Mellor AL, Munn DH, Zhou G. (2010) Chemotherapy rescues tumor-driven aberrant CD4+ T-cell differentiation and restores an activated polyfunctional helper phenotype. Blood 115(12) 2397-406
Ding ZC, Lu X, Yu M, Lemos H, Huang L, Chandler P, Liu K, Walters M, Krasinski A, Mack M, Blazar BR, Mellor AL, Munn DH, Zhou G. (2014) Immunosuppressive myeloid cells induced by chemotherapy attenuate antitumor CD4+ T-cell responses through the PD-1-PD-L1 axis. Cancer Res 74(13) 3441-53
Ding ZC, Lu X, Yu M, Lemos H, Huang L, Chandler P, Liu K, Walters M, Krasinski A, Mack M, Blazar BR, Mellor AL, Munn DH, Zhou G. (2014) Immunosuppressive myeloid cells induced by chemotherapy attenuate antitumor CD4+ T-cell responses through the PD-1-PD-L1 axis. Cancer Res 74(13) 3441-53
Ding ZC, Huang L, Blazar BR, Yagita H, Mellor AL, Munn DH, Zhou G. (2012) Polyfunctional CD4⁺ T cells are essential for eradicating advanced B-cell lymphoma after chemotherapy. Blood 120(11) 2229-39
Ding ZC, Huang L, Blazar BR, Yagita H, Mellor AL, Munn DH, Zhou G. (2012) Polyfunctional CD4⁺ T cells are essential for eradicating advanced B-cell lymphoma after chemotherapy. Blood 120(11) 2229-39
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Resouce detail information
(request form)
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http://www2.brc.riken.jp/lab/animal/detail.php?brc_no=RBRC00904
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Organization |
Experimental Animal Division, RIKEN BioResource Research Center |
Person in charge |
YOSHIKI Atsushi |
Postal Code |
305-0074 |
Address |
3-1-1 Koyadai, Tsukuba, Ibaraki, Japan |
Phone |
029-836-5264 |
FAX |
029-836-9010 |
E-mail |
animal@brc.riken.jp
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URL |
https://mus.brc.riken.jp
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Other information |
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