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Resource Information cacnb1

Resource Information
Organism	Zebrafish
strain or clone	Strain
Category	Mutant
Resource name	cacnb1
Availability	Available
Features	Allele : mi90 Information : The cacnb1 mutants are called relaxed mutants.The mutant phenotype results from a non-sense mutation in the zebrafish cacnb1 gene that encodes the voltage-gated calcium channel beta1 subunit. The zebrafish cacnb1 gene is expressed in skeletal muscles, PNS and CNS. The mutants are immotile due to a defect in excitation-contraction coupling of skeletal muscle. Gene : cacnb1(Cacnb1) Publications : Zhou W et al (2006) Cell Calcium 39(3),227-36 Taxonomy : Siluriformes Reference : Linsley JW, Hsu IU, Wang W, Kuwada JY. (2017) Transport of the alpha subunit of the voltage gated L-type calcium channel through the sarcoplasmic reticulum occurs prior to localization to triads and requires the beta subunit but not Stac3 in skeletal muscles. Traffic 18(9) 622-632
Resouce detail information (request form)	http://shigen.nig.ac.jp/zebrafish/strainDetailAction.do?strainId=349

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Distributors information
Organization	Developmental Gene Regulation. RIKEN Brain Science Institute
Person in charge	OKAMOTO Hitoshi
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E-mail	hitoshi.okamoto@riken.jp
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