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Category: 自然突然変異系統
Category: 自然突然変異系統
| Strain Name : |
PROD-Cacna1a<tg-rol>/NemOdaRbrc |
| 遺伝子名 : |
Cacna1a,CACNA1A |
| 種名 : |
Mus musculus |
| 疾患情報 : |
Developmental Biology Research,Genetics Research,Neurobiology Research |
| 提供条件 : |
凍結胚より作出したマウスを2~4ヶ月以内に提供可能,凍結胚を1ヶ月以内に提供可能 |
| Status : |
凍結胚 |
| Taxonomy : |
Mus musculus
|
| リファレンス : |
Fukumoto N, Obama Y, Kitamura N, Niimi K, Takahashi E, Itakura C, Shibuya I. (2009) Hypoalgesic behaviors of P/Q-type voltage-gated Ca2+ channel mutant mouse, rolling mouse Nagoya. Neuroscience 160(1) 165-73
Tian X, Zhou Y, Gao L, He G, Jiang W, Li W, Takahashi E. (2013) Analysis of ischemic neuronal injury in Cav2.1 channel α1 subunit mutant mice. Biochem Biophys Res Commun 434(1) 60-4
Kim TY, Niimi K, Takahashi E. (2017) Analysis of the protective effects of the α
Niimi K, Han Y, Zhou Y, Yoshimoto T, Dai F, Teng X, Tian X, Li W, Takahashi E. (2014) Blockade of Cav2.1-mediated NMDA receptor signaling disrupts conditioned fear extinction. Behav Brain Res 259 45-9
Fukumoto N, Kitamura N, Niimi K, Takahashi E, Itakura C, Shibuya I. (2012) Ca2+ channel currents in dorsal root ganglion neurons of P/Q-type voltage-gated Ca2+ channel mutant mouse, rolling mouse Nagoya. Neurosci Res 73(3) 199-206
Goriely S, Molle C, Nguyen M, Albarani V, Haddou NO, Lin R, De Wit D, Flamand V, Willems F, Goldman M. (2006) Interferon regulatory factor 3 is involved in Toll-like receptor 4 (TLR4)- and TLR3-induced IL-12p35 gene activation. Blood 107(3) 1078-84
Takahashi E, Niimi K, Itakura C. (2010) Interaction between Ca(v)2.1alpha (1) and CaMKII in Ca (v)2.1alpha (1) mutant mice, Rolling Nagoya. J Mol Neurosci 41(2) 223-9
Takahashi E, Niimi K, Itakura C. (2009) Motor coordination impairment in aged heterozygous rolling Nagoya, Cav2.1 mutant mice. Brain Res 1279 50-7
Takahashi E, Niimi K, Itakura C. (2009) Age-related spatial and nonspatial short-term memory in Cav2.1alpha1 mutant mice, Rolling Nagoya. Behav Brain Res 204(1) 241-5
Takahashi E, Niimi K. (2009) Spatial learning deficit in aged heterozygous Cav2.1 channel mutant mice, rolling mouse Nagoya. Exp Gerontol 44(4) 274-9
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Category: 自然突然変異系統
Category: 自然突然変異系統
| Strain Name : |
BALB/cPas-Reln<rl-Orl>/PasRbrc |
| 遺伝子名 : |
Reln |
| 種名 : |
Mus musculus |
| 提供条件 : |
凍結胚より作出したマウスを2~4ヶ月以内に提供可能,凍結胚を1ヶ月以内に提供可能 |
| Status : |
凍結胚 |
| Taxonomy : |
Mus musculus
|
| リファレンス : |
Sobue A, Kushima I, Nagai T, Shan W, Kohno T, Aleksic B, Aoyama Y, Mori D, Arioka Y, Kawano N, Yamamoto M, Hattori M, Nabeshima T, Yamada K, Ozaki N. (2018) Genetic and animal model analyses reveal the pathogenic role of a novel deletion of RELN in schizophrenia. Sci Rep 8(1) 13046
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Category: 自然突然変異系統
| Strain Name : |
PIC/Nem-Pdn/+ |
| 遺伝子名 : |
Gli3 |
| 種名 : |
Mus musculus |
| 疾患情報 : |
Developmental Biology Research |
| 提供条件 : |
生体マウスを1~3ヶ月以内に提供可能,凍結胚を1ヶ月以内に提供可能 |
| Status : |
生体,凍結胚 |
| Taxonomy : |
Mus musculus
|
| リファレンス : |
Imai T, Yamazaki T, Kobayakawa R, Kobayakawa K, Abe T, Suzuki M, Sakano H. (2009) Pre-target axon sorting establishes the neural map topography. Science 325(5940) 585-90
Ueta E, Kodama M, Sumino Y, Kurome M, Ohta K, Katagiri R, Naruse I. (2010) Gender-dependent differences in the incidence of ochratoxin A-induced neural tube defects in the Pdn/Pdn mouse. Congenit Anom (Kyoto) 50(1) 29-39
Naruse I, Ueta E, Sumino Y, Ogawa M, Ishikiriyama S. (2010) Birth defects caused by mutations in human GLI3 and mouse Gli3 genes. Congenit Anom (Kyoto) 50(1) 1-7
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Category: 自然突然変異系統
| Strain Name : |
C.Cg-Cpox<nct>/JmsRbrc |
| 遺伝子名 : |
Cpox |
| 種名 : |
Mus musculus |
| 疾患情報 : |
Sensorineural Research |
| 提供条件 : |
凍結胚より作出したマウスを2~4ヶ月以内に提供可能 |
| Status : |
凍結胚 |
| Taxonomy : |
Mus musculus
|
| リファレンス : |
Liu C, Miyahara H, Dai J, Cui X, Li Y, Kang X, Higuchi K, Mori M. (2022) Involvement of increased endoplasmic reticulum stress in the development of cataracts in BALB.NCT-Cpox
Shoji H, Kiniwa Y, Okuyama R, Yang M, Higuchi K, Mori M. (2015) A nonsense nucleotide substitution in the oculocutaneous albinism II gene underlies the original pink-eyed dilution allele (Oca2(p)) in mice. Exp Anim 64(2) 171-9
Xiaojing Kang, Shin Shimada, Hiroki Miyahara, Keiichi Higuchi, Masayuki Mori (2023) BALB.NCT-Cpox is a unique mouse model of hereditary coproporphyria Molecular Genetics and Metabolism Reports 35 100964
Narita M, Wang Y, Kita A, Omi N, Yamada Y, Hiai H. (2002) Genetic analysis of Nakano Cataract and its modifier genes in mice. Exp Eye Res 75(6) 745-51
Mori M, Gotoh S, Taketani S, Hiai H, Higuchi K. (2013) Hereditary cataract of the Nakano mouse: Involvement of a hypomorphic mutation in the coproporphyrinogen oxidase gene. Exp Eye Res 112 45-50
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Category: 自然突然変異系統
Category: 自然突然変異系統
Category: 自然突然変異系統
Category: 自然突然変異系統
| Strain Name : |
B6.Cg-Foxn1<nu>/Nrs |
| 遺伝子名 : |
Foxn1 |
| 種名 : |
Mus musculus |
| 提供条件 : |
凍結精子より作出したマウスを2~4ヶ月以内に提供可能 ,凍結精子を1ヶ月以内に提供可能,凍結胚を1ヶ月以内に提供可能 |
| Status : |
凍結胚,凍結精子 |
| Taxonomy : |
Mus musculus
|
| リファレンス : |
Yanagihara T, Sanematsu F, Sato T, Uruno T, Duan X, Tomino T, Harada Y, Watanabe M, Wang Y, Tanaka Y, Nakanishi Y, Suyama M, Yoshinori F. (2015) Intronic regulation of Aire expression by Jmjd6 for self-tolerance induction in the thymus. Nat Commun 6 8820
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Category: 自然突然変異系統
Category: 自然突然変異系統
| Strain Name : |
BALB/c-Scn1a<+/-> |
| 遺伝子名 : |
Scn1a |
| 種名 : |
Mus musculus |
| 疾患情報 : |
Mouse Models for Human Disease,Neurobiology Research |
| 提供条件 : |
凍結精子より作出したマウスを2~4ヶ月以内に提供可能 ,凍結精子を1ヶ月以内に提供可能 |
| Status : |
凍結精子 |
| Taxonomy : |
Mus musculus
|
| リファレンス : |
Yuhei Takado, Hiroyuki Takuwa, Kazuaki Sampei, Takuya Urushihata, Manami Takahashi, Masafumi Shimojo, Shoko Uchida, Nobuhiro Nitta, Sayaka Shibata, Keisuke Nagashima, Yoshihiro Ochi, Maiko Ono, Jun Maeda, Yutaka Tomita, Naruhiko Sahara, Jamie Near, Ichio Aoki, Kazuhisa Shibata, Makoto Higuchi () MRS-measured Glutamate versus GABA reflects excitatory versus inhibitory neural activities in awake mice
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Category: 自然突然変異系統
| Strain Name : |
RLC/Stm |
| 遺伝子名 : |
Dock5 |
| 種名 : |
Mus musculus |
| 疾患情報 : |
Mouse Models for Human Disease,Sensorineural Research |
| 提供条件 : |
凍結胚より作出したマウスを2~4ヶ月以内に提供可能,凍結胚を1ヶ月以内に提供可能 |
| Status : |
凍結胚 |
| Taxonomy : |
Mus musculus
|
| リファレンス : |
Omi N, Kiyokawa E, Matsuda M, Kinoshita K, Yamada S, Yamada K, Matsushima Y, Wang Y, Kawai J, Suzuki M, Hayashizaki Y, Hiai H. (2008) Mutation of Dock5, a member of the guanine exchange factor Dock180 superfamily, in the rupture of lens cataract mouse. Exp Eye Res 86(5) 828-34
Hiai H, Tsuruyama T, Yamada Y. (2003) Pre-B lymphomas in SL/Kh mice: a multifactorial disease model. Cancer Sci 94(10) 847-50
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Category: 自然突然変異系統
| Strain Name : |
C3H/HeSn-Ttf/+tf |
| 遺伝子名 : |
Itpr3,T |
| 種名 : |
Mus musculus |
| 疾患情報 : |
Dermatology Research,Developmental Biology Research |
| 提供条件 : |
凍結胚より作出したマウスを2~4ヶ月以内に提供可能,凍結胚を1ヶ月以内に提供可能 |
| Status : |
凍結胚 |
| Taxonomy : |
Mus musculus
|
| リファレンス : |
Hatakeyama Y, Saito N, Mii Y, Takada R, Shinozuka T, Takemoto T, Naoki H, Takada S. (2023) Intercellular exchange of Wnt ligands reduces cell population heterogeneity during embryogenesis. Nat Commun 14(1) 1924
Hatakeyama Y, Saito N, Mii Y, Takada R, Shinozuka T, Takemoto T, Naoki H, Takada S. (2023) Intercellular exchange of Wnt ligands reduces cell population heterogeneity during embryogenesis. Nat Commun 14(1) 1924
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Category: 自然突然変異系統
| Strain Name : |
C57BL/6-Prkdc<scid>/Rbrc |
| 遺伝子名 : |
Prkdc |
| 種名 : |
Mus musculus |
| 疾患情報 : |
Immunology and Inflammation Research |
| 提供条件 : |
凍結精子より作出したマウスを2~4ヶ月以内に提供可能 ,凍結精子を1ヶ月以内に提供可能 |
| Status : |
凍結胚,凍結精子 |
| Taxonomy : |
Mus musculus
|
| リファレンス : |
Ishino T, Kawashima S, Tanji E, Ueno T, Ueda Y, Ogasawara S, Sato K, Mano H, Ishihara S, Kato N, Kawazu M, Togashi Y. (2023) Somatic mutations can induce a noninflamed tumour microenvironment via their original gene functions, despite deriving neoantigens. Br J Cancer
Ishino T, Kawashima S, Tanji E, Ueno T, Ueda Y, Ogasawara S, Sato K, Mano H, Ishihara S, Kato N, Kawazu M, Togashi Y. (2023) Somatic mutations can induce a noninflamed tumour microenvironment via their original gene functions, despite deriving neoantigens. Br J Cancer
Kawase K, Kawashima S, Nagasaki J, Inozume T, Tanji E, Kawazu M, Hanazawa T, Togashi Y. (2023) High Expression of MHC Class I Overcomes Cancer Immunotherapy Resistance Due to IFNγ Signaling Pathway Defects. Cancer Immunol Res OF1-OF14
Kawase K, Kawashima S, Nagasaki J, Inozume T, Tanji E, Kawazu M, Hanazawa T, Togashi Y. (2023) High Expression of MHC Class I Overcomes Cancer Immunotherapy Resistance Due to IFNγ Signaling Pathway Defects. Cancer Immunol Res OF1-OF14
Kemmotsu N, Zhu L, Nagasaki J, Otani Y, Ueda Y, Dansako H, Fang Y, Date I, Togashi Y. (2023) Combination therapy with hydrogen peroxide and irradiation promotes an abscopal effect in mouse models. Cancer Sci
Kemmotsu N, Zhu L, Nagasaki J, Otani Y, Ueda Y, Dansako H, Fang Y, Date I, Togashi Y. (2023) Combination therapy with hydrogen peroxide and irradiation promotes an abscopal effect in mouse models. Cancer Sci
Nagasaki J, Togashi Y, Sugawara T, Itami M, Yamauchi N, Yuda J, Sugano M, Ohara Y, Minami Y, Nakamae H, Hino M, Takeuchi M, Nishikawa H. (2020) The critical role of CD4+ T cells in PD-1 blockade against MHC-II-expressing tumors such as classic Hodgkin lymphoma. Blood Adv 4(17) 4069-4082
Nagasaki J, Togashi Y, Sugawara T, Itami M, Yamauchi N, Yuda J, Sugano M, Ohara Y, Minami Y, Nakamae H, Hino M, Takeuchi M, Nishikawa H. (2020) The critical role of CD4+ T cells in PD-1 blockade against MHC-II-expressing tumors such as classic Hodgkin lymphoma. Blood Adv 4(17) 4069-4082
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Category: 自然突然変異系統
| Strain Name : |
C57BL/6-W<sh>/W<sh> |
| 遺伝子名 : |
Kit |
| 種名 : |
Mus musculus |
| 疾患情報 : |
Dermatology Research,Immunology and Inflammation Research |
| 提供条件 : |
生体マウスを1~3ヶ月以内に提供可能,凍結精子を1ヶ月以内に提供可能,凍結胚を1ヶ月以内に提供可能 |
| Status : |
生体,凍結胚,凍結精子 |
| Taxonomy : |
Mus musculus
|
| リファレンス : |
Hitomi K, Tahara-Hanaoka S, Miki H, Iwata K, Shibayama S, Kubo M, Shibuya A. (2018) Allergin-1 on mast cells suppresses house dust mite-induced airway hyperresponsiveness in mice. Int Immunol 30(9) 429-434
Hitomi K, Tahara-Hanaoka S, Miki H, Iwata K, Shibayama S, Kubo M, Shibuya A. (2018) Allergin-1 on mast cells suppresses house dust mite-induced airway hyperresponsiveness in mice. Int Immunol 30(9) 429-434
Nakamura T, Maeda S, Horiguchi K, Maehara T, Aritake K, Choi BI, Iwakura Y, Urade Y, Murata T. (2015) PGD2 deficiency exacerbates food antigen-induced mast cell hyperplasia. Nat Commun 6 7514
Nakamura T, Maeda S, Horiguchi K, Maehara T, Aritake K, Choi BI, Iwakura Y, Urade Y, Murata T. (2015) PGD2 deficiency exacerbates food antigen-induced mast cell hyperplasia. Nat Commun 6 7514
Yoshida K, Tanihara S, Miyashita Y, Obayashi K, Ito MA, Yamamoto K, Imai T, Matsuoka I. (2022) P2X4 receptor stimulation enhances MrgprB2-mediated mast cell activation and pseudoallergic reactions in mice. Sci Rep 12(1) 18613
Yoshida K, Tanihara S, Miyashita Y, Obayashi K, Ito MA, Yamamoto K, Imai T, Matsuoka I. (2022) P2X4 receptor stimulation enhances MrgprB2-mediated mast cell activation and pseudoallergic reactions in mice. Sci Rep 12(1) 18613
Murata T, Aritake K, Matsumoto S, Kamauchi S, Nakagawa T, Hori M, Momotani E, Urade Y, Ozaki H. (2011) Prostagladin D2 is a mast cell-derived antiangiogenic factor in lung carcinoma. Proc Natl Acad Sci U S A 108(49) 19802-7
Murata T, Aritake K, Matsumoto S, Kamauchi S, Nakagawa T, Hori M, Momotani E, Urade Y, Ozaki H. (2011) Prostagladin D2 is a mast cell-derived antiangiogenic factor in lung carcinoma. Proc Natl Acad Sci U S A 108(49) 19802-7
Ohneda K, Moriguchi T, Ohmori S, Ishijima Y, Satoh H, Philipsen S, Yamamoto M. (2014) Transcription factor GATA1 is dispensable for mast cell differentiation in adult mice. Mol Cell Biol 34(10) 1812-26
Ohneda K, Moriguchi T, Ohmori S, Ishijima Y, Satoh H, Philipsen S, Yamamoto M. (2014) Transcription factor GATA1 is dispensable for mast cell differentiation in adult mice. Mol Cell Biol 34(10) 1812-26
Iwanaga K, Nakamura T, Maeda S, Aritake K, Hori M, Urade Y, Ozaki H, Murata T. (2014) Mast cell-derived prostaglandin D2 inhibits colitis and colitis-associated colon cancer in mice. Cancer Res 74(11) 3011-9
Iwanaga K, Nakamura T, Maeda S, Aritake K, Hori M, Urade Y, Ozaki H, Murata T. (2014) Mast cell-derived prostaglandin D2 inhibits colitis and colitis-associated colon cancer in mice. Cancer Res 74(11) 3011-9
Schuler P, Contassot E, Irla M, Hugues S, Preynat-Seauve O, Beermann F, Donda A, French LE, Huard B. (2008) Direct presentation of a melanocyte-associated antigen in peripheral lymph nodes induces cytotoxic CD8+ T cells. Cancer Res 68(20) 8410-8
Schuler P, Contassot E, Irla M, Hugues S, Preynat-Seauve O, Beermann F, Donda A, French LE, Huard B. (2008) Direct presentation of a melanocyte-associated antigen in peripheral lymph nodes induces cytotoxic CD8+ T cells. Cancer Res 68(20) 8410-8
Nakahashi-Oda C, Tahara-Hanaoka S, Shoji M, Okoshi Y, Nakano-Yokomizo T, Ohkohchi N, Yasui T, Kikutani H, Honda S, Shibuya K, Nagata S, Shibuya A. (2012) Apoptotic cells suppress mast cell inflammatory responses via the CD300a immunoreceptor. J Exp Med 209(8) 1493-503
Nakahashi-Oda C, Tahara-Hanaoka S, Shoji M, Okoshi Y, Nakano-Yokomizo T, Ohkohchi N, Yasui T, Kikutani H, Honda S, Shibuya K, Nagata S, Shibuya A. (2012) Apoptotic cells suppress mast cell inflammatory responses via the CD300a immunoreceptor. J Exp Med 209(8) 1493-503
Murata A, Hikosaka M, Yoshino M, Zhou L, Hayashi SI. (2019) Kit-independent mast cell adhesion mediated by Notch. Int Immunol 31(2) 69-79
Murata A, Hikosaka M, Yoshino M, Zhou L, Hayashi SI. (2019) Kit-independent mast cell adhesion mediated by Notch. Int Immunol 31(2) 69-79
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Category: 自然突然変異系統
| Strain Name : |
MSM.NC-Kit<W-v>/OhnotRbrc |
| 遺伝子名 : |
Kit |
| 種名 : |
Mus musculus molossinus |
| 提供条件 : |
凍結胚より作出したマウスを2~4ヶ月以内に提供可能,凍結精子を1ヶ月以内に提供可能 |
| Status : |
凍結胚,凍結精子 |
| Taxonomy : |
Mus musculus
|
| リファレンス : |
Mochida K, Hasegawa A, Otaka N, Hama D, Furuya T, Yamaguchi M, Ichikawa E, Ijuin M, Taguma K, Hashimoto M, Takashima R, Kadota M, Hiraiwa N, Mekada K, Yoshiki A, Ogura A. (2014) Devising assisted reproductive technologies for wild-derived strains of mice: 37 strains from five subspecies of Mus musculus. PLoS One 9(12) e114305
Mochida K, Hasegawa A, Otaka N, Hama D, Furuya T, Yamaguchi M, Ichikawa E, Ijuin M, Taguma K, Hashimoto M, Takashima R, Kadota M, Hiraiwa N, Mekada K, Yoshiki A, Ogura A. (2014) Devising assisted reproductive technologies for wild-derived strains of mice: 37 strains from five subspecies of Mus musculus. PLoS One 9(12) e114305
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Category: 近交系統
| Strain Name : |
KOR1-ls<Stm> |
| 遺伝子名 : |
Edn3 |
| 種名 : |
Mus musculus molossinus |
| 提供条件 : |
凍結胚より作出したマウスを2~4ヶ月以内に提供可能 |
| Status : |
凍結胚 |
| Taxonomy : |
Mus musculus
|
| リファレンス : |
Mochida K, Hasegawa A, Otaka N, Hama D, Furuya T, Yamaguchi M, Ichikawa E, Ijuin M, Taguma K, Hashimoto M, Takashima R, Kadota M, Hiraiwa N, Mekada K, Yoshiki A, Ogura A. (2014) Devising assisted reproductive technologies for wild-derived strains of mice: 37 strains from five subspecies of Mus musculus. PLoS One 9(12) e114305
Mochida K, Hasegawa A, Otaka N, Hama D, Furuya T, Yamaguchi M, Ichikawa E, Ijuin M, Taguma K, Hashimoto M, Takashima R, Kadota M, Hiraiwa N, Mekada K, Yoshiki A, Ogura A. (2014) Devising assisted reproductive technologies for wild-derived strains of mice: 37 strains from five subspecies of Mus musculus. PLoS One 9(12) e114305
Mochida K, Hasegawa A, Otaka N, Hama D, Furuya T, Yamaguchi M, Ichikawa E, Ijuin M, Taguma K, Hashimoto M, Takashima R, Kadota M, Hiraiwa N, Mekada K, Yoshiki A, Ogura A. (2014) Devising assisted reproductive technologies for wild-derived strains of mice: 37 strains from five subspecies of Mus musculus. PLoS One 9(12) e114305
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Category: 近交系統
| Strain Name : |
MSM;MA-Tyr<c>/RinRbrc |
| 遺伝子名 : |
Tyr |
| 種名 : |
Mus musculus molossinus |
| 提供条件 : |
凍結胚より作出したマウスを2~4ヶ月以内に提供可能 |
| Status : |
凍結胚 |
| Taxonomy : |
Mus musculus
|
| リファレンス : |
Mochida K, Hasegawa A, Otaka N, Hama D, Furuya T, Yamaguchi M, Ichikawa E, Ijuin M, Taguma K, Hashimoto M, Takashima R, Kadota M, Hiraiwa N, Mekada K, Yoshiki A, Ogura A. (2014) Devising assisted reproductive technologies for wild-derived strains of mice: 37 strains from five subspecies of Mus musculus. PLoS One 9(12) e114305
Mochida K, Hasegawa A, Otaka N, Hama D, Furuya T, Yamaguchi M, Ichikawa E, Ijuin M, Taguma K, Hashimoto M, Takashima R, Kadota M, Hiraiwa N, Mekada K, Yoshiki A, Ogura A. (2014) Devising assisted reproductive technologies for wild-derived strains of mice: 37 strains from five subspecies of Mus musculus. PLoS One 9(12) e114305
Mochida K, Hasegawa A, Otaka N, Hama D, Furuya T, Yamaguchi M, Ichikawa E, Ijuin M, Taguma K, Hashimoto M, Takashima R, Kadota M, Hiraiwa N, Mekada K, Yoshiki A, Ogura A. (2014) Devising assisted reproductive technologies for wild-derived strains of mice: 37 strains from five subspecies of Mus musculus. PLoS One 9(12) e114305
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分譲可
