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Resource count: 6,595,109

Resource Information Strain No : RBRC00388

Resource Information
Organism Mice
strain or clone Strain
Category spontaneous mutation
Resource name RBRC00388
Availability Available
Features
Strain Name : PROD-Cacna1a<tg-rol>/NemOdaRbrc
Gene : Cacna1a,CACNA1A
Species : Mus musculus
Disease : Developmental Biology Research,Genetics Research,Neurobiology Research
Conditions for use : Recovered litters from cryopreserved embryos (2 to 4 months),Cryopreserved embryos (within 1 month)
Status : Frozen embryos
Taxonomy : Mus musculus
Reference : Fukumoto N, Obama Y, Kitamura N, Niimi K, Takahashi E, Itakura C, Shibuya I. (2009) Hypoalgesic behaviors of P/Q-type voltage-gated Ca2+ channel mutant mouse, rolling mouse Nagoya. Neuroscience 160(1) 165-73
Tian X, Zhou Y, Gao L, He G, Jiang W, Li W, Takahashi E. (2013) Analysis of ischemic neuronal injury in Cav2.1 channel α1 subunit mutant mice. Biochem Biophys Res Commun 434(1) 60-4
Kim TY, Niimi K, Takahashi E. (2017) Analysis of the protective effects of the α
Niimi K, Han Y, Zhou Y, Yoshimoto T, Dai F, Teng X, Tian X, Li W, Takahashi E. (2014) Blockade of Cav2.1-mediated NMDA receptor signaling disrupts conditioned fear extinction. Behav Brain Res 259 45-9
Fukumoto N, Kitamura N, Niimi K, Takahashi E, Itakura C, Shibuya I. (2012) Ca2+ channel currents in dorsal root ganglion neurons of P/Q-type voltage-gated Ca2+ channel mutant mouse, rolling mouse Nagoya. Neurosci Res 73(3) 199-206
Goriely S, Molle C, Nguyen M, Albarani V, Haddou NO, Lin R, De Wit D, Flamand V, Willems F, Goldman M. (2006) Interferon regulatory factor 3 is involved in Toll-like receptor 4 (TLR4)- and TLR3-induced IL-12p35 gene activation. Blood 107(3) 1078-84
Takahashi E, Niimi K, Itakura C. (2010) Interaction between Ca(v)2.1alpha (1) and CaMKII in Ca (v)2.1alpha (1) mutant mice, Rolling Nagoya. J Mol Neurosci 41(2) 223-9
Takahashi E, Niimi K, Itakura C. (2009) Motor coordination impairment in aged heterozygous rolling Nagoya, Cav2.1 mutant mice. Brain Res 1279 50-7
Takahashi E, Niimi K, Itakura C. (2009) Age-related spatial and nonspatial short-term memory in Cav2.1alpha1 mutant mice, Rolling Nagoya. Behav Brain Res 204(1) 241-5
Takahashi E, Niimi K. (2009) Spatial learning deficit in aged heterozygous Cav2.1 channel mutant mice, rolling mouse Nagoya. Exp Gerontol 44(4) 274-9
Resouce detail information
(request form)
http://www2.brc.riken.jp/lab/animal/detail.php?brc_no=RBRC00388

Distributors information
Organization Experimental Animal Division, RIKEN BioResource Research Center
Person in charge YOSHIKI Atsushi
Postal Code 305-0074
Address 3-1-1 Koyadai, Tsukuba, Ibaraki, Japan
Phone 029-836-5264
FAX 029-836-9010
E-mail animal@brc.riken.jp
URL https://mus.brc.riken.jp
Other information